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'Smart' nanoparticles identify, target and kill cancer cells

'Smart' nanoparticles identify, target and kill cancer cells

Another weapon in the arsenal against cancer has been invented at Cornell: nanoparticles that identify, target and kill specific cancer cells while leaving healthy cells alone.

Led by Carl Batt, the Liberty Hyde Bailey Professor of Food Science, the researchers synthesized nanoparticles -- shaped something like a dumbbell -- made of gold sandwiched between two pieces of iron oxide. They then attached antibodies that target a molecule found only in colorectal cancer cells to the particles.

Colorectal Cancer Test Targets Cancer Stem Cells in Blood

Researchers in Japan have developed an experimental blood test that may help identify patients withcolorectal cancer who have an aggressive form of the disease and could benefit from additional therapy after surgery.The test screens the blood for tumor cells that have three molecular markers, including a marker for the protein CD133. This marker is found on some cells that have the properties of stem cells, such as the ability to self renew. Without CD133, the test results were not informative, suggesting to the researchers the importance of this cancer stem cell marker.